Statins are now well established as powerful and favorable lipid-modifying drugs. They are primarily used for individuals with coronary artery disease or an abnormal lipid panel, and result in major decreases in morbidity and mortality.
Passive leg raising (PLR), a rapidly reversible maneuver that simulates rapid volume expansion by putting several hundred milliliters of fluid back into the circulation, has been shown to predict fluid responsiveness in mechanically ventilated patients.
With increased emphasis on evidence-based medicine during the last dozen years has come the implicit assumption that the availability of more and better evidence on how disease should be diagnosed and managed will lead to better patient care.
Passive leg raising (PLR), a rapidly reversible maneuver that simulates rapid volume expansion by putting several hundred milliliters of fluid back into the circulation, has been shown to predict fluid responsiveness in mechanically ventilated patients.
In this issue: FDA is reviewing safety of TZDs; SSRI use with tamoxifen; Metformin smells like fish; FDA Actions.
